Science and Research

Neutrophil extracellular trap formation is regulated by CXCR2 in COPD neutrophils

  • Pedersen, F.
  • Waschki, B.
  • Marwitz, S.
  • Goldmann, T.
  • Kirsten, A.
  • Malmgren, A.
  • Rabe, K. F.
  • Uddin, M.
  • Watz, H.

Keywords

  • Aged
  • Extracellular Traps/*metabolism
  • Humans
  • Middle Aged
  • Neutrophils/drug effects/metabolism
  • Pulmonary Disease, Chronic Obstructive/*drug therapy
  • Pyrimidines/*therapeutic use
  • Receptors, Interleukin-8B/*antagonists & inhibitors
  • Sputum/cytology
  • Sulfonamides/*therapeutic use
  • interest: B. Waschki reports grants from AstraZeneca. Conflict of interest: A.
  • Kirsten reports grants from AstraZeneca, and personal fees from AstraZeneca and
  • Boehringer Ingelheim. Conflict of interest: A. Malmgren is an employee of
  • AstraZeneca. Conflict of interest: K. Rabe reports grants from AstraZeneca, and
  • personal fees from AstraZeneca, BerlinChemie, Boehringer Ingelheim, Chiesi,
  • Novartis, SanofiAventis, and Teva. Conflict of interest: M. Uddin is an employee
  • of AstraZeneca. Conflict of interest: H. Watz reports grants from AstraZeneca,
  • personal fees and non-financial support from AstraZeneca, GlaxoSmithKline and
  • Novartis, and personal fees from BerlinChemie, Boehringer Ingelheim and Chiesi.
Publication details
DOI: 10.1183/13993003.00970-2017
Journal: The European respiratory journal
Number: 4
Work Type: Original
Location: ARCN
Disease Area: COPD
Partner / Member: FZB, Ghd
Access-Number: 29449427
See publication on PubMed


chevron-down