Implantable infusion pumps might improve the convenience and safety of intravenous treprostinil for pulmonary arterial hypertension. The LENUS Pro(R) pump (approved in Europe) has a fixed flow rate. Based on 126 pumps and 2853 refills, we retrospectively analyzed the actual flow rate from 09/2010 to 09/2018. A relevant flow rate variance is evident after three years; therefore, flow rate monitoring and dose adjustment are mandatory.
- Richter, M. J.
- Harutyunova, S.
- Bollmann, T.
- Classen, S.
- Fuge, J.
- Gall, H.
- Gerhardt, F.
- Ghofrani, H. A.
- Gunkel, H.
- Grunig, E.
- Halank, M.
- Heine, A.
- Klose, H.
- Lange, T. J.
- Neurohr, C.
- Nickolaus, K.
- Opitz, C. F.
- Rosenkranz, S.
- Seyfarth, H. J.
- Tello, K.
- Ewert, R.
- Olsson, K. M.
Keywords
- implantable infusion pump
- prostanoid
- pulmonary hypertension
- treatment
