Impact of Inspiratory Pressure Rise Time on Lung-Emptying in Time Controlled Adaptive Ventilation

Background: The airway pressure release ventilation (APRV)-based time controlled adaptive ventilation (TCAV) protocol can potentially minimize ventilator-induced lung injury (VILI). Inspiratory pressure rise time (IPRT) is a parameter available in pressure-controlled ventilation modes, yet its role within TCAV remains unclear. We hypothesized that varying IPRTs impact lung emptying and associated ventilatory parameters (driving pressure [

• Neetz, B.
• Rehn, P.
• Kraus, N.
• Schmidt, W.
• Reinhardt, L.
• Flohr, T.
• Laußer, C.
• Weigand, M. A.
• Fiedler-Kalenka, M. O.