Science and Research

A Phase IIb Randomized Clinical Study of an Anti-α(v)β(6) Monoclonal Antibody in Idiopathic Pulmonary Fibrosis

Rationale: Treatment options for idiopathic pulmonary fibrosis (IPF) are limited. Objectives: To evaluate the efficacy and safety of BG00011, an anti-

  • Raghu, G.
  • Mouded, M.
  • Chambers, D. C.
  • Martinez, F. J.
  • Richeldi, L.
  • Lancaster, L. H.
  • Hamblin, M. J.
  • Gibson, K. F.
  • Rosas, I. O.
  • Prasse, A.
  • Zhao, G.
  • Serenko, M.
  • Novikov, N.
  • McCurley, A.
  • Bansal, P.
  • Stebbins, C.
  • Arefayene, M.
  • Ibebunjo, S.
  • Violette, S. M.
  • Gallagher, D.
  • Behr, J.

Keywords

  • Humans
  • *Idiopathic Pulmonary Fibrosis/drug therapy
  • Antibodies, Monoclonal/therapeutic use
  • Treatment Outcome
  • Double-Blind Method
  • Immunoglobulin G
  • anti-αvβ6 IgG1 monoclonal antibody
  • idiopathic pulmonary fibrosis
  • randomized clinical trial
  • safety
  • treatment efficacy
Publication details
DOI: 10.1164/rccm.202112-2824OC
Journal: Am J Respir Crit Care Med
Pages: 1128-1139 
Number: 9
Work Type: Original
Location: CPC-M
Disease Area: DPLD
Partner / Member: KUM
Access-Number: 35771569

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