Targeting Proteases in Cystic Fibrosis Lung Disease. Paradigms, Progress, and Potential

Keywords

• Chloride Channel Agonists/therapeutic use
• Cysteine Proteases/*metabolism
• Cysteine Proteinase Inhibitors/therapeutic use
• Cystic Fibrosis/drug therapy/*metabolism
• Cystic Fibrosis Transmembrane Conductance Regulator/metabolism
• Humans
• Leukocyte Elastase/metabolism
• Matrix Metalloproteinase Inhibitors/therapeutic use
• Matrix Metalloproteinases/*metabolism
• Molecular Targeted Therapy
• Peptide Hydrolases/metabolism
• Protease Inhibitors/therapeutic use
• Serine Proteases/*metabolism
• Serine Proteinase Inhibitors/therapeutic use