Fluid Restriction in Patients with Pulmonary Arterial Hypertension and Right Heart Failure

INTRODUCTION: In pulmonary arterial hypertension (PAH), right heart (RH) failure is associated with high mortality and poor prognosis. The objective of this cohort study was to assess, whether reduction of fluid intake is associated with RH size and clinical outcome in PAH patients. METHODS: A retrospective, exploratory analysis of patients with invasively diagnosed PAH and signs of fluid retention who were routinely clinically monitored for 8.4 ± 5.3 months including fluid uptake and signs of RH failure was performed. Patients were advised to reduce fluid uptake to a maximum of 2 L per day (L/day) according to clinical routine. Clinical characteristics of patients with normal fluid intake <2 L/day vs. high fluid intake

• Benjamin, N.
• Resag, C.
• Xanthouli, P.
• Harutyunova, S.
• Eichstaedt, C.
• Egenlauf, B.
• Grünig, E.