Science and Research

The Human Organ Atlas

We present the Human Organ Atlas (HOA), an open data repository making accessible multiscale three-dimensional imaging of human organs. The repository also provides software tools and training resources enabling worldwide access, sharing, and analysis of these datasets, facilitating further research and the continued expansion of the HOA. The images are generated using a synchrotron imaging technique, hierarchical phase-contrast tomography (HiP-CT), that uses the ESRF's Extremely Brilliant Source, spanning whole-organ imaging at ~20 micrometers/voxel with local volumes of interest within intact organs imaged down to ~1 micrometer/voxel. This offers a comprehensive exploration of human anatomy, providing unparalleled insights into intricate structures and spatial relationships. The HOA offers researchers, clinicians, and educators a valuable resource for anatomical study, image analysis, medical education, and large-scale data mining.

  • Walsh, C. L.
  • Brunet, J.
  • Stansby, D.
  • Gaisné, G.
  • Zhou, Y.
  • Ackermann, M.
  • Bellier, A.
  • Berruyer, C.
  • Bocciarelli, A.
  • Bodin, M.
  • de Bakker, B. S.
  • Dejea, H.
  • Antolinos, A. M.
  • Engel, K.
  • Götz, A.
  • Jacob, J.
  • Jonigk, D.
  • Purzycka, J.
  • Urban, T.
  • Verleden, S. E.
  • Xue, R.
  • Tafforeau, P.
  • Lee, P. D.

Keywords

  • Humans
  • Imaging, Three-Dimensional
  • *Atlases as Topic
  • Software
  • Tomography, X-Ray Computed
Publication details
DOI: 10.1126/sciadv.adz2240
Journal: Sci Adv
Pages: eadz2240 
Number: 11
Work Type: Original
Location: BREATH
Disease Area: PLI
Partner / Member: MHH
Access-Number: 41811956


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