Allergic diseases, including atopic dermatitis (AD), food allergy (FA), asthma and allergic rhinitis/rhinoconjunctivitis (AR) are the most prevalent chronic childhood diseases affecting one in four children in the Western world (1). This global health problem imposes a significant burden on patient's quality of life (2), family, health care and society. The current state of knowledge assumes that complex interactions between genetic and environmental factors influence a child´s immune maturation prior to the development of allergic diseases (3). To date, no reliable predictions of allergy development exists. Current scores, including clinical features and laboratory data, have only reached limited specificity and/or sensitivity (4).
- Eckert, J. K.
- Kahle, J.
- Böck, A.
- Zeber, K.
- Urner, K.
- Greiner, W.
- Kreimeier, S.
- Beyer, K.
- Dobbertin-Welsch, J.
- Hamelmann, E.
- Gellhaus, I.
- Schorlemer, C.
- Kabesch, M.
- Kheiroddin, P.
- von Mutius, E.
- Depner, M.
- Walter, D.
- Hansen, G.
- DeStefano, S.
- Schnadt, S.
- Schaub, B.
Keywords
- Allergy
- Biomarker
- Childhood
- Cohorts
- Health-Related Quality of Life
- Prediction
- Survey
