Science and Research

A drug screen with approved compounds identifies amlexanox as a novel Wnt/β-catenin activator inducing lung epithelial organoid formation

  • Costa, R.
  • Wagner, D. E.
  • Doryab, A.
  • De Santis, M. M.
  • Schorpp, K.
  • Rothenaigner, I.
  • Lehmann, M.
  • Baarsma, H. A.
  • Liu, X.
  • Schmid, O.
  • Campillos, M.
  • Yildirim, AÖ
  • Hadian, K.
  • Königshoff, M.

Keywords

  • Organoids
  • Regenerative Medicine
  • Wnt/β-catenin signaling pathway
  • amlexanox
  • chronic obstructive pulmonary disease
  • emphysema
Publication details
DOI: 10.1111/bph.15581
Journal: Br J Pharmacol
Work Type: Original
Location: CPC-M
Disease Area: COPD
Partner / Member: HMGU
Access-Number: 34089180

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