Science and Research

"I Can Taste It, But Sometimes It's Disgusting" Cross-sectional Study on the Influence of SARS-CoV-2 Infections, Both Acute and Postinfection, in Comparison to Other Respiratory Infections on Taste and Smell Perception

BACKGROUND: Subjective smell and taste disorders were frequently reported during and after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (SCI), but mostly investigated by interviews/questionnaires. METHODS: We examined from 07/2021 to 10/2022 objective (U-Sniff/Taste Strips) and subjective (questionnaire-based) impairment in children with (1) acute SCI (AC; n = 30) and other upper respiratory tract infection (n = 34), (2) children with (PI+; n = 28)/without (PI-; n = 13) remaining symptoms >/=12 weeks after SCI and (3) as control 18 noninfected children. Children with acute infections were examined blinded regarding the results of their SARS-CoV-2 polymerase chain reaction. Statistics: X(2), F test, Kruskal-Wallis, P < 0.05. RESULTS: Abnormal test results occurred in up to a fifth of children. Severe hyposmia was detected in 17% of children with upper respiratory tract infection and 21% in PI+, severe hypogeusia was mostly in AC children (18%), followed by both postinfection groups (PI+ 12%, PI- 10%). Subjective smell impairment was significantly more frequent in PI+ (32% vs.

  • Mallon, C.
  • Brinkmann, F.
  • Schlegtendal, A.
  • Maier, C.
  • Lucke, T.
  • Hoffmann, A. T.
  • Keywords

    • Humans
    • *COVID-19/complications/physiopathology
    • Cross-Sectional Studies
    • Male
    • Female
    • Child
    • Child, Preschool
    • *Respiratory Tract Infections/complications/physiopathology
    • SARS-CoV-2
    • *Taste Disorders/etiology
    • Adolescent
    • *Olfaction Disorders/etiology
    • *Taste
    • Smell/physiology
    • Infant
    • airway infection
    • children
    • taste disturbance
    Publication details
    DOI: 10.1097/INF.0000000000005116
    Journal: Pediatr Infect Dis J
    Pages: 510-515 
    Number: 6
    Work Type: Original
    Location: Assoziierter Partner
    Disease Area: PALI
    Partner / Member: UKSH (Lübeck)
    Access-Number: 41430536
    See publication on PubMed


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