Science and Research

[Expert Meeting on COPD: Personalized Treatment of COPD - Wishful Thinking or Reality?]

Chronic obstructive pulmonary disease (COPD) is considered to be a complex and heterogeneous disease comprising multiple components. Its clinical presentation, pattern of functional disturbance, disease presentation and pathology varies tremendously between individuals despite the common feature of incompletely reversible airflow obstruction. It is therefore widely accepted that COPD is characterized by discriminable phenotypes that represent specific patterns of these disease features. COPD phenotypes are believed to correlate with outcome parameters such as severity of symptoms, exacerbations, functional loss or death and to require different treatment algorithms.This survey is the result of presentations that were given during an expert conference. It highlights the significance of major comorbidities, genetic, morphologic and inflammatory COPD-phenotypes and their impact on disease progression and treatment modalities.

  • Lorenz, J.
  • Bals, R.
  • Ewert, R.
  • Jany, B.
  • Koczulla, A. R.
  • Kohnlein, T.
  • Randerath, W. J.
  • Steinkamp, G.
  • Watz, H.
  • Welte, T.

Keywords

  • Congresses as Topic
  • Expert Testimony
  • Genetic Predisposition to Disease/genetics
  • Germany
  • Molecular Targeted Therapy/*methods
  • Precision Medicine/*methods
  • Pulmonary Disease, Chronic Obstructive/diagnosis/*genetics/*therapy
Publication details
DOI: 10.1055/s-0042-112044
Journal: Pneumologie (Stuttgart, Germany)
Pages: 638-650 
Number: 10
Work Type: Other
Location: ARCN, BREATH, UGMLC
Disease Area: COPD
Partner / Member: Ghd, MHH, UMR
Access-Number: 27723914
See publication on PubMed

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