Science and Research

Early Pulmonary Interstitial Emphysema in Preterm Neonates-Respiratory Management and Case Report in Nonventilated Very Low Birth Weight Twins

Early pulmonary interstitial emphysema in extreme preterm neonates is closely linked with respiratory distress syndrome and exposure to mechanical ventilation. In severe cases, maintaining adequate gas exchange aiming to avoid further lung damage and other neonatal morbidities associated with systemic/pulmonary hypoperfusion, prolonged hypoxia, and respiratory acidosis can be challenging and requires in-depth knowledge into the pathophysiology of the disease. Herein, we report on very low birth weight twins who developed early pulmonary interstitial emphysema during noninvasive respiratory support. We further review the current evidence from the literature, specifically addressing on possible preventive measures and the respiratory management options of this acute pulmonary disease in high-risk neonates.

  • Gronbach, J.
  • Ehrhardt, H.
  • Zimmer, K. P.
  • Waitz, M.

Keywords

  • antenatal steroids
  • noninvasive ventilation
  • pulmonary interstitial emphysema
  • surfactant
  • very-low-birth-weight infants
Publication details
DOI: 10.1055/s-0038-1648253
Journal: AJP reports
Pages: e99-e105 
Number: 2
Work Type: Original
Location: UGMLC
Disease Area: DPLD
Partner / Member: JLU
Access-Number: 29765788
See publication on PubMed

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