Long-term oxygen therapy in precapillary pulmonary hypertension - SOPHA study

Current guidelines recommend oxygen (O(2)) supplementation in patients with pulmonary hypertension (PH), despite scarce data on long-term O(2) therapy (LTOT). The aim of this prospective, randomized, controlled trial was to investigate the effect of LTOT in patients with precapillary PH on exercise capacity, clinical parameters and hemodynamics. Patients with precapillary PH under stable therapy and O(2) desaturations at rest and/or during exercise were randomized to receive LTOT (

• Benjamin, N.
• Echampati, I.
• Harutyunova, S.
• Eichstaedt, C. A.
• Egenlauf, B.
• Ulrich, S.
• Grünig, E.
• Xanthouli, P.