Science and Research

Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging

Multiplexed antibody-based imaging enables the detailed characterization of molecular and cellular organization in tissues. Advances in the field now allow high-parameter data collection (>60 targets); however, considerable expertise and capital are needed to construct the antibody panels employed by these methods. Organ mapping antibody panels are community-validated resources that save time and money, increase reproducibility, accelerate discovery and support the construction of a Human Reference Atlas.

  • Quardokus, E. M.
  • Saunders, D. C.
  • McDonough, E.
  • Hickey, J. W.
  • Werlein, C.
  • Surrette, C.
  • Rajbhandari, P.
  • Casals, A. M.
  • Tian, H.
  • Lowery, L.
  • Neumann, E. K.
  • Björklund, F.
  • Neelakantan, T. V.
  • Croteau, J.
  • Wiblin, A. E.
  • Fisher, J.
  • Livengood, A. J.
  • Dowell, K. G.
  • Silverstein, J. C.
  • Spraggins, J. M.
  • Pryhuber, G. S.
  • Deutsch, G.
  • Ginty, F.
  • Nolan, G. P.
  • Melov, S.
  • Jonigk, D.
  • Caldwell, M. A.
  • Vlachos, I. S.
  • Muller, W.
  • Gehlenborg, N.
  • Stockwell, B. R.
  • Lundberg, E.
  • Snyder, M. P.
  • Germain, R. N.
  • Camarillo, J. M.
  • Kelleher, N. L.
  • Börner, K.
  • Radtke, A. J.
Publication details
DOI: 10.1038/s41592-023-01846-7
Journal: Nat Methods
Pages: 1174-1178 
Number: 8
Work Type: Original
Location: BREATH
Disease Area: PLI
Partner / Member: MHH
Access-Number: 37468619

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