Mediterranean diet component oleic acid decreases systemic impact of periodontal Porphyromonas gingivalis-infection in age: addressing role of stress resistance and microbiome

Periodontitis (PD) is an age-associated infectious periodontal disease driven by dysbiosis and hyperinflammatory host response, resulting in bone and tissue loss. Often linked to systemic inflammatory comorbidities, modulating host response emerged as promising clinical target. This study investigates whether nutritional intervention mitigates age-associated systemic impact of oral infection with PD key pathogen Porphyromonas gingivalis. Young (5 weeks) and aged (

• Döding, A.
• Wurschi, L.
• Zubiria-Barrera, C.
• Klassert, T. E.
• Bereuter, L.
• Rao, Z.
• Bär, A. K.
• Domuncu, A.
• Koeberle, A.
• Noels, H.
• Slevogt, H.
• Sigusch, B.
• Schulze-Späte, U.