Deep Mouse Brain Two-Photon Near-Infrared Fluorescence Imaging Using a Superconducting Nanowire Single-Photon Detector Array

Two-photon microscopy (2PM) has become an important tool in biology to study the structure and function of intact tissues in vivo. However, adult mammalian tissues such as the mouse brain are highly scattering, thereby putting fundamental limits on the achievable imaging depth, which typically reside at around 600-800

• Tamimi, A.
• Caldarola, M.
• Hambura, S.
• Boffi, J. C.
• Noordzij, N.
• Los, J. W. N.
• Guardiani, A.
• Kooiman, H.
• Wang, L.
• Kieser, C.
• Braun, F.
• Castaneda, M. A. U.
• Fognini, A.
• Prevedel, R.