Nanoparticle-Exposure-Triggered Virus Reactivation Induces Lung Emphysema in Mice

Nanoparticles (NPs) released from engineered materials or combustion processes as well as persistent herpesvirus infection are omnipresent and are associated with chronic lung diseases. Previously, we showed that pulmonary exposure of a single dose of soot-like carbonaceous NPs (CNPs) or fiber-shaped double-walled carbon nanotubes (DWCNTs) induced an increase of lytic virus protein expression in mouse lungs latently infected with murine

• Han, L.
• Haefner, V.
• Yu, Y.
• Han, B.
• Ren, H.
• Irmler, M.
• Beckers, J.
• Liu, Q.
• Feuchtinger, A.
• Yildirim, A. O.
• Adler, H.
• Stoeger, T.