Science and Research

Explorations of Agonist Selectivity for the α9* nAChR with Novel Substituted Carbamoyl/Amido/Heteroaryl Dialkylpiperazinium Salts and Their Therapeutic Implications in Pain and Inflammation

There is an urgent need for nonopioid treatments for chronic and neuropathic pain to provide effective alternatives amid the escalating opioid crisis. This study introduces novel compounds targeting the

  • Andleeb, H.
  • Papke, R. L.
  • Stokes, C.
  • Richter, K.
  • Herz, S. M.
  • Chiang, K.
  • Kanumuri, S. R. R.
  • Sharma, A.
  • Damaj, M. I.
  • Grau, V.
  • Horenstein, N. A.
  • Thakur, G. A.
Publication details
DOI: 10.1021/acs.jmedchem.3c02429
Journal: J Med Chem
Work Type: Original
Location: UGMLC
Disease Area: PALI
Partner / Member: JLU
Access-Number: 38748608

DZL Engagements

chevron-down