Guidance for chest-CT in children and adults with cystic fibrosis: A European perspective

The European Cystic Fibrosis Society-Clinical Trials Network (ECFS-CTN) herein proposes guidance for the use of chest CT-scans for the regular monitoring of lung disease in CF. Statements were completed in a 3-step process: the questions were identified via an anonymous online survey, followed by a comprehensive literature search, and a final Delphi process. The guidance recommends the use of ultra-low dose CT scans (effective radiation dose, 0.08 mSv; equivalent to 2 to 4 chest X-rays), tracking of patients' cumulative radiation and effective communication strategies using "de-medicalized" information for shared decision making. Chest CT scans (with lung volume monitoring) are not recommended systematically in both children and adults. Ultimate responsibility for justifying a chest CT scan lies with the individual professionals directly involved, the final decision being influenced by indications, costs, expertise, available material, resources and/or the patient's values, as well as possible impact on treatment modalities.

• Fayon, M.
• Hill, K.
• Waldron, M.
• Messore, B.
• Riberi, L.
• Svedberg, M.
• Lammertyn, E.
• Fustik, S.
• Gramegna, A.
• Stahl, M.
• Kerpel-Fronius, A.
• Balbi, M.
• Ciet, P.
• Chassagnon, G.
• Ferrero, C.
• Burgel, P. R.
• Sutharsan, S.
• Opitz, M.
• Andrinopoulou, E. R.
• Dournes, G.
• Maher, M.
• Duckers, J.
• Tiddens, H.
• Sermet, I.