Drug allergy to CFTR modulator therapy associated with lumacaftor-specific CD4(+) T lymphocytes

CAPSULE SUMMARY: Allergy to CFTR modulators will have a high impact on affected patients in the future. This work demonstrates the use of in vitro cell culture methods to detect the causative component of CFTR modulator combinations.

• Roehmel, J. F.
• Ogese, M. O.
• Rohrbach, A.
• Mall, M. A.
• Naisbitt, D. J.