Science and Research

The neonatal window of opportunity-early priming for life

he concept of the neonatal window of opportunity assigns the early postnatal period a critical role for life-long host-microbial and immune homeostasis. It is supported by epidemiological evidence that links postnatal environmental exposure with disease susceptibility and mechanisms in the neonate host that facilitate the postnatal transposition, establish a stable microbiome and promote immune maturation. During the conference on "The neonatal window of opportunity - early priming for life", postnatal microbiome and immune maturation, epidemiological evidence and fundamental mechanisms were discussed to identify new targets for future preventive and interventional measures.

  • Renz, H.
  • Adkins, B. D.
  • Bartfeld, S.
  • Blumberg, R. S.
  • Farber, D. L.
  • Garssen, J.
  • Ghazal, P.
  • Hackam, D. J.
  • Marsland, B. J.
  • McCoy, K. D.
  • Penders, J.
  • Prinz, I.
  • Verhasselt, V.
  • von Mutius, E.
  • Weiser, J. N.
  • Wesemann, D. R.
  • Hornef, M. W.
Publication details
DOI: 10.1016/j.jaci.2017.11.019
Journal: The Journal of allergy and clinical immunology
Pages: 1212-1214 
Number: 4
Work Type: Other
Location: BREATH, CPC-M, UGMLC
Disease Area: AA
Partner / Member: LMU, MHH, UMR
Access-Number: 29247715
See publication on PubMed

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