Science and Research

Macrophage fatty acid metabolism under chronic hypoxia shapes

Hypoxia in solid tumors is associated with poor outcomes because of metabolic adaptations that support tumor cell survival and alter immune cell function. However, the metabolic and phenotypic adaptations of macrophages (M

  • Guerrero Ruiz, V. M.
  • Khabaza, A.
  • Bauer, R.
  • Aliraj, B.
  • Mansouri, S.
  • Meyer, S. P.
  • Palmer, M. A.
  • Winter, H.
  • Klotz, L. V.
  • Elewa, M. A. F.
  • Kur, I. M.
  • Angioni, C.
  • Mojaradfar, R.
  • Hahnefeld, L.
  • Savai, R.
  • Fuhrmann, D.
  • Weigert, A.
  • Brüne, B.

Keywords

  • Cancer
  • Human metabolism
  • Immune response
Publication details
DOI: 10.1016/j.isci.2025.113025
Journal: iScience
Pages: 113025 
Number: 8
Work Type: Original
Location: TLRC, UGMLC
Disease Area: LC
Partner / Member: JLU, MPI-BN, UKHD
Access-Number: 40697830


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