Lipoteichoic acid (LTA) is an important cell envelope compound of Gram-positive bacteria. LTA isolated from allergy-protective Staphylococcus sciuri W620 strain was characterized by chemical analyses as well as 1D and 2D NMR experiments. Compositional analyses indicated the presence of glycerol (Gro), phosphate-Gro, alanine-Gro, glucose (Glc) and fatty acids. The studied strain produced LTA with backbone composed of glycerol-phosphate repeating units only substituted with d-alanine (Ala) and the lipid anchor, typically for genus Staphyloccocus, possessing the structure beta-d-Glcp(1-->6)- beta-d-Glcp(1-->3)-1,2-diacyl-sn-Gro.
- Duda, K. A.
- Petersen, S.
- Holst, O.
Keywords
- Carbohydrate Sequence
- Lipopolysaccharides/*chemistry
- Staphylococcus/*chemistry
- Teichoic Acids/*chemistry
- Allergy-protection
- LTA structure
- NMR analysis
- Staphylococcus sciuri
