Science and Research

[Alpha-Gal-associated delayed red meat anaphylaxis as an occupational disease]

In a 30-year-old chef with recurrent delayed angioedema history as well as the experimental detection of IgE antibodies against galactose-alpha-(1,3)-galactose (alpha-Gal) pointed to alpha-Gal as the causative agent. The diagnosis, therefore, was delayed anaphylaxis due to alpha-Gal. Because of the potential relationship to his profession, we submitted a dermatologist's report BK 5101 to the liability and insurance association, whereupon his contract of employment was terminated without notice. As a consequence, we reported an occupational disease. This case demonstrates an underdiagnosed, potentially life-threatening allergy to the disaccharide alpha-Gal in red meat as an occupational disease.

  • Anemuller, W.
  • Mohr, M.
  • Brans, R.
  • Homann, A.
  • Jappe, U.

Keywords

  • Accident insurance
  • Allergy
  • Angioedema
  • Delayed hypersensitivity, type 1
  • Hypersensitivity
Publication details
DOI: 10.1007/s00105-018-4224-4
Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
Pages: 848-852 
Number: 10
Work Type: Other
Location: ARCN
Disease Area: AA
Partner / Member: FZB
Access-Number: 29951852
See publication on PubMed

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