Science and Research

B cells latently infected with murine gammaherpesvirus 68 (MHV-68) are present in the mouse thymus-A step toward immune evasion?

We show that latently gammaherpesvirus-infected B cells are present in the thymus. This could result in a functional T-cell tolerance against certain viral epitopes. It is conceivable that also antigens from other viruses or pathogens may be conveyed to the thymus for their immune evasion.

  • Yamano, T.
  • Steinert, M.
  • Steer, B.
  • Klein, L.
  • Hammerschmidt, W.
  • Adler, H.
Publication details
DOI: 10.1002/eji.201847886
Journal: Eur J Immunol
Pages: 351-352 
Number: 2
Work Type: Original
Location: CPC-M
Disease Area: PALI
Partner / Member: HMGU, LMU
Access-Number: 30488950
See publication on PubMed

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