Association of Long-term Exposure to Ambient Air Pollutants With Risk Factors for Cardiovascular Disease in China

Importance: Which cardiometabolic risk factors (eg, hypertension, type 2 diabetes, overweight or obesity, and dyslipidemia) are more sensitive to long-term exposure to ambient air pollution and whether participants with these conditions are more susceptible to the cardiovascular effects of air pollution remain unclear. Objectives: To evaluate the associations among long-term exposure to air pollutants, cardiometabolic risk factors, and cardiovascular disease (CVD) prevalence. Design, Setting, and Participants: This population-based cross-sectional study was conducted from April 1 through December 31, 2009, in 3 cities in Northeastern China. Participants were adults aged 18 to 74 years who had lived in study area for 5 years or longer. Data analysis was performed from May 1 through December 31, 2018. Exposures: Long-term (2006-2008) exposure to air pollutants was measured using a spatiotemporal statistical model (particulate matter with an aerodynamic diameter of

Yang, B. Y.

Guo, Y.

Markevych, I.

Qian, Z. M.

Bloom, M. S.

Heinrich, J.

Dharmage, S. C.

Rolling, C. A.

Jordan, S. S.

Komppula, M.

Leskinen, A.

Bowatte, G.

Li, S.

Chen, G.

Liu, K. K.

Zeng, X. W.

Hu, L. W.

Dong, G. H.