Is computed tomography suitable for detecting lung cancer at a very early stage and thus still well treatable? Scientists at the German Cancer Research Center have investigated this with the LUSI study started in 2007. The results of the study, which is funded by the Deutsche Forschungsgemeinschaft and the Dietmar Hopp Foundation, are now available: Taken together, the screening slightly but not significantly reduced lung cancer mortality in both sexes. In contrast, the researchers observed a significant 69 percent reduction in relative risk among women. The results confirm comparable European studies which, taken together, provide strong arguments for the introduction of systematic lung cancer screening for high-risk groups.

Although research is advancing with great strides, the life expectancy of people with cystic fibrosis (CF) is still significantly reduced. The genetic disorder causes severe infections of the lungs associated with the increasing accumulation of mucus clogging the airways. CF is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, resulting in the dysfunction of a chloride channel in somatic cells. Researchers have now succeeded in taking an initial step toward the development of a potential gene therapy for cystic fibrosis.

May 9, 2019
Prematurely born infants often develop a chronic lung disease known as Bronchopulmonary Dysplasia (BPD)...

Einen Schwerpunkt der diesjährigen 125. Jahrestagung der Deutschen Gesellschaft für Innere Medizin e.V. (DGIM) vom 4. bis 7. Mai in Wiesbaden bilden die Deutschen Zentren für Gesundheitsforschung (DZG). In wissenschaftlichen Symposien und am Gemeinschaftsstand stellen sie ihre aktuellen Forschungsergebnisse vor.

April 26, 2019

Pulmonary Arterial Hypertension (PAH) is a progressive, fatal disease of the pulmonary vasculature...

The DZL was represented with an information desk at the 60th Congress of the German Respiratory Society (DGP), which took place in Munich from March 13–16, 2019...

Studying the lung microbiome requires a specialist approach to sampling, laboratory techniques and statistical analysis. In the latest ERS Monograph, Guest Editors Michael Cox, Markus Ege and Erika von Mutius bring together chapters that introduce the techniques used and discuss how respiratory sampling, 16S rRNA gene sequencing, metagenomics and the application of ecological theory can be used to examine the respiratory microbiome. The book examines the different components of the respiratory microbiome, and considers a range of contexts (from paediatrics to disease at all ages) and respiratory diseases, including asthma, COPD, interstitial lung diseases, cancer and many more.

In “The Lung Microbiome”, the Guest Editors and authors have produced a unique and comprehensive introduction to the field, which will help develop understanding about the concepts and application of this novel area of research.

Book details:
Title: The Lung Microbiome
Guest Editors: Michael J. Cox, Markus J. Ege and Erika von Mutius
Chief Editor: Robert Bals (outgoing), John R. Hurst (incoming)
Print copies available from:
Print ISBN: 978-1-84984-101-6
Online ISBN: 978-1-84984-102-3

Around 500 scientists, physicians, and junior researchers from five sites attended the 8th DZL Annual Meeting on February 7 and 8 at the Rosengarten Mannheim. This means that the number of participants has risen again this year. Special attention was paid to the outstanding developments in the promotion of junior scientists.

The new technology can be used to understand the therapeutic success of inhaled active substances.

The German Center for Lung Research (DZL), one of the six German Centers for Health Research (DZG), follows the current discussion on the health risk posed by air pollutants with great concern. Using the occasion of the DZL Annual Meeting in Mannheim, the DZL notes the following with regard to its position:

Upcoming Events

23.08.2019 - 24.08.2019
Summer School Pädiatrische Pneumologie 2019
07.09.2019 - 07.09.2019
12. Symposium Lunge
11.09.2019 - 13.09.2019
ETRS Annual Meeting 2019