{"id":32202,"date":"2021-11-29T15:33:14","date_gmt":"2021-11-29T14:33:14","guid":{"rendered":"https:\/\/dzl.de\/?p=32202"},"modified":"2022-03-10T16:16:47","modified_gmt":"2022-03-10T15:16:47","slug":"young-investigator-merit-award-for-michal-mastalerz","status":"publish","type":"post","link":"https:\/\/dzl.de\/en\/news\/young-investigator-merit-award-for-michal-mastalerz\/","title":{"rendered":"Young Investigator Merit Award for Michal Mastalerz"},"content":{"rendered":"<p><em>The \u2018Young Investigator Merit Award\u2019 2021 by the Research Training Group \u2018Targets in Toxicology\u2019 at LMU Munich goes to PhD student Michal Mastalerz (CPC-M, Munich). This award is endowed with funds of a total of 50.000 EUR consisting of a 6 months post-doctoral position and project-related consumables. On\u00a0November 26, at the occasion of the GRK symposium, Mastalerz was awarded one of two\u00a0Young Investigator Merit Awards and presented his work.<\/em><\/p>\n<p>In CPC-M\u2018s Staab-Weijnitz' lab (Helmholtz Munich) Michal Mastalerz is working on cigarette smoke as a contributor to many chronic lung diseases. He has set up a methodology to\u00a0validate cigarette smoke exposure systems of airway epithelial cells, the first line of defense in the response to cigarette smoke. Using this methodology (see publication below), Mastalerz found that two exposure settings using cigarette smoke extract were similarly effective as whole cigarette smoke exposure.<\/p>\n<p>He has now applied this model which led to the identification of several novel cigarette smoke-regulated proteins and pathways. Using this preliminary data, he successfully submitted a proposal for the Young Investigator Merit Award to investigate function and effects of these novel\u00a0cigarette smoke-induced\u00a0mechanisms in more detail and more complex culture systems.<\/p>\n<p>Michal Mastalerz is also a fellow of the DZL Academy, an initiative of the German Center for Lung Research for young scientists.<\/p>\n<p>The Research Training Group \u201cTargets in Toxicology - Deciphering Therapeutic Targets in Lung Toxicology\u201d was founded 2018 and is a structured Ph.D. program which brings together twelve research partners in the Munich region. Principal investigators from the LMU Munich, Helmholtz Zentrum M\u00fcnchen, Technische Universit\u00e4t M\u00fcnchen, and the Bundeswehr Institute of Pharmacology and Toxicology have teamed up to acquire an in-depth mechanistic understanding of toxic lung injury and to develop the new concept of \u201cprecision toxicology\u201d in acute and chronic toxic lung injury.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Further information:<\/strong><\/p>\n<p>Original publication:\u00a0<a href=\"https:\/\/journals.physiology.org\/doi\/abs\/10.1152\/ajplung.00091.2021\" target=\"_blank\" rel=\"noopener\"><span style=\"font-size: 12pt;\">Validation of in vitro models for smoke exposure of primary human bronchial epithelial cells<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Early-career scientist of DZL Academy investigates the impact of cigarette smoke on the epithelial cells in the lung.<\/p>\n","protected":false},"author":24,"featured_media":32210,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_seopress_robots_primary_cat":"none","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"categories":[28],"tags":[304,284],"class_list":["post-32202","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-dzl-academy-en","tag-prizes-awards"],"acf":[],"_links":{"self":[{"href":"https:\/\/dzl.de\/en\/wp-json\/wp\/v2\/posts\/32202","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dzl.de\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dzl.de\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dzl.de\/en\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/dzl.de\/en\/wp-json\/wp\/v2\/comments?post=32202"}],"version-history":[{"count":7,"href":"https:\/\/dzl.de\/en\/wp-json\/wp\/v2\/posts\/32202\/revisions"}],"predecessor-version":[{"id":34470,"href":"https:\/\/dzl.de\/en\/wp-json\/wp\/v2\/posts\/32202\/revisions\/34470"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dzl.de\/en\/wp-json\/wp\/v2\/media\/32210"}],"wp:attachment":[{"href":"https:\/\/dzl.de\/en\/wp-json\/wp\/v2\/media?parent=32202"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dzl.de\/en\/wp-json\/wp\/v2\/categories?post=32202"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dzl.de\/en\/wp-json\/wp\/v2\/tags?post=32202"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}